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Encephalopathy-causing mutations in Gβ1 (GNB1) alter regulation of neuronal GIRK channels.

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Title: Encephalopathy-causing mutations in Gβ1 (GNB1) alter regulation of neuronal GIRK channels.
Authors: Reddy HP; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India., Yakubovich D; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.; Department of Pediatrics, Schneider Children's Medical Center, Petah Tikva, Israel., Keren-Raifman T; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Tabak G; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Tsemakhovich VA; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Pedersen MH; Departments of Psychiatry & Molecular Pharmacology and Therapeutics, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.; NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, København, Denmark., Shalomov B; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Colombo S; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY10032, USA., Goldstein DB; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY10032, USA.; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY10032, USA., Javitch JA; Departments of Psychiatry & Molecular Pharmacology and Therapeutics, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA., Bera AK; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India., Dascal N; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 6997801, Israel.
Source: IScience [iScience] 2021 Aug 21; Vol. 24 (9), pp. 103018. Date of Electronic Publication: 2021 Aug 21 (Print Publication: 2021).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
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  Data: Encephalopathy-causing mutations in Gβ<subscript>1</subscript> (GNB1) alter regulation of neuronal GIRK channels.
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  Data: <searchLink fieldCode="AU" term="%22Reddy+HP%22">Reddy HP</searchLink>; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India.<br /><searchLink fieldCode="AU" term="%22Yakubovich+D%22">Yakubovich D</searchLink>; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.; Department of Pediatrics, Schneider Children's Medical Center, Petah Tikva, Israel.<br /><searchLink fieldCode="AU" term="%22Keren-Raifman+T%22">Keren-Raifman T</searchLink>; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.<br /><searchLink fieldCode="AU" term="%22Tabak+G%22">Tabak G</searchLink>; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.<br /><searchLink fieldCode="AU" term="%22Tsemakhovich+VA%22">Tsemakhovich VA</searchLink>; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.<br /><searchLink fieldCode="AU" term="%22Pedersen+MH%22">Pedersen MH</searchLink>; Departments of Psychiatry & Molecular Pharmacology and Therapeutics, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.; NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, København, Denmark.<br /><searchLink fieldCode="AU" term="%22Shalomov+B%22">Shalomov B</searchLink>; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.<br /><searchLink fieldCode="AU" term="%22Colombo+S%22">Colombo S</searchLink>; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY10032, USA.<br /><searchLink fieldCode="AU" term="%22Goldstein+DB%22">Goldstein DB</searchLink>; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY10032, USA.; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY10032, USA.<br /><searchLink fieldCode="AU" term="%22Javitch+JA%22">Javitch JA</searchLink>; Departments of Psychiatry & Molecular Pharmacology and Therapeutics, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bera+AK%22">Bera AK</searchLink>; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India.<br /><searchLink fieldCode="AU" term="%22Dascal+N%22">Dascal N</searchLink>; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 6997801, Israel.
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