Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level.
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| Title: | Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level. |
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| Authors: | John L; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Poos AM; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Brobeil A; Department of Pathology, Heidelberg University Hospital, Heidelberg, Germany., Schinke C; Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Huhn S; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Prokoph N; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Lutz R; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany., Wagner B; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Zangari M; Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Tirier SM; Division of Chromatin Networks, German Cancer Research Center (DKFZ) and BioQuant, Heidelberg, Germany., Mallm JP; Single Cell Open Lab, German Cancer Research Center (DKFZ) and BioQuant, Heidelberg, Germany., Schumacher S; Division of Chromatin Networks, German Cancer Research Center (DKFZ) and BioQuant, Heidelberg, Germany., Vonficht D; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany., Solé-Boldo L; Institute of Health (BIH) at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; Department of Hematology, Oncology and Tumor Immunology, Charité University Medicine, Berlin, Germany., Quick S; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Steiger S; Division of Chromatin Networks, German Cancer Research Center (DKFZ) and BioQuant, Heidelberg, Germany., Przybilla MJ; Division Computational Genomics and Systems Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Wellcome Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK., Bauer K; Single Cell Open Lab, German Cancer Research Center (DKFZ) and BioQuant, Heidelberg, Germany., Baumann A; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Hemmer S; Department of Orthopedic Surgery, Heidelberg University Hospital, Heidelberg, Germany., Rehnitz C; Department of Radiology, Heidelberg University Hospital, Heidelberg, Germany., Lückerath C; Department of Radiology, Heidelberg University Hospital, Heidelberg, Germany., Sachpekidis C; Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center (DKFZ), Heidelberg, Germany., Mechtersheimer G; Department of Pathology, Heidelberg University Hospital, Heidelberg, Germany., Haberkorn U; Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany., Dimitrakopoulou-Strauss A; Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center (DKFZ), Heidelberg, Germany., Reichert P; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Barlogie B; Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Müller-Tidow C; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Heidelberg, Germany., Goldschmidt H; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Heidelberg, Germany., Hillengass J; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Rasche L; Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany.; Mildred Scheel Early Career Center (MSNZ), University Hospital of Würzburg, Würzburg, Germany., Haas SF; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Institute of Health (BIH) at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; Department of Hematology, Oncology and Tumor Immunology, Charité University Medicine, Berlin, Germany., van Rhee F; Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Rippe K; Division of Chromatin Networks, German Cancer Research Center (DKFZ) and BioQuant, Heidelberg, Germany., Raab MS; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Sauer S; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Weinhold N; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany. niels.weinhold@med.uni-heidelberg.de.; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany. niels.weinhold@med.uni-heidelberg.de.; Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA. niels.weinhold@med.uni-heidelberg.de. |
| Source: | Nature communications [Nat Commun] 2023 Aug 17; Vol. 14 (1), pp. 5011. Date of Electronic Publication: 2023 Aug 17. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 37591845 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22John+L%22">John L</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Poos+AM%22">Poos AM</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Brobeil+A%22">Brobeil A</searchLink>; Department of Pathology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schinke+C%22">Schinke C</searchLink>; Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22Huhn+S%22">Huhn S</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Prokoph+N%22">Prokoph N</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lutz+R%22">Lutz R</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Wagner+B%22">Wagner B</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Zangari+M%22">Zangari M</searchLink>; Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22Tirier+SM%22">Tirier SM</searchLink>; Division of Chromatin Networks, German Cancer Research Center (DKFZ) and BioQuant, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Mallm+JP%22">Mallm JP</searchLink>; Single Cell Open Lab, German Cancer Research Center (DKFZ) and BioQuant, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schumacher+S%22">Schumacher S</searchLink>; Division of Chromatin Networks, German Cancer Research Center (DKFZ) and BioQuant, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Vonficht+D%22">Vonficht D</searchLink>; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Solé-Boldo+L%22">Solé-Boldo L</searchLink>; Institute of Health (BIH) at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; Department of Hematology, Oncology and Tumor Immunology, Charité University Medicine, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Quick+S%22">Quick S</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Steiger+S%22">Steiger S</searchLink>; Division of Chromatin Networks, German Cancer Research Center (DKFZ) and BioQuant, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Przybilla+MJ%22">Przybilla MJ</searchLink>; Division Computational Genomics and Systems Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Wellcome Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Bauer+K%22">Bauer K</searchLink>; Single Cell Open Lab, German Cancer Research Center (DKFZ) and BioQuant, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Baumann+A%22">Baumann A</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Hemmer+S%22">Hemmer S</searchLink>; Department of Orthopedic Surgery, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Rehnitz+C%22">Rehnitz C</searchLink>; Department of Radiology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lückerath+C%22">Lückerath C</searchLink>; Department of Radiology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Sachpekidis+C%22">Sachpekidis C</searchLink>; Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Mechtersheimer+G%22">Mechtersheimer G</searchLink>; Department of Pathology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Haberkorn+U%22">Haberkorn U</searchLink>; Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Dimitrakopoulou-Strauss+A%22">Dimitrakopoulou-Strauss A</searchLink>; Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Reichert+P%22">Reichert P</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Barlogie+B%22">Barlogie B</searchLink>; Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22Müller-Tidow+C%22">Müller-Tidow C</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Goldschmidt+H%22">Goldschmidt H</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Hillengass+J%22">Hillengass J</searchLink>; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Rasche+L%22">Rasche L</searchLink>; Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany.; Mildred Scheel Early Career Center (MSNZ), University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Haas+SF%22">Haas SF</searchLink>; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Institute of Health (BIH) at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; Department of Hematology, Oncology and Tumor Immunology, Charité University Medicine, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22van+Rhee+F%22">van Rhee F</searchLink>; Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22Rippe+K%22">Rippe K</searchLink>; Division of Chromatin Networks, German Cancer Research Center (DKFZ) and BioQuant, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Raab+MS%22">Raab MS</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Sauer+S%22">Sauer S</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Weinhold+N%22">Weinhold N</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany. niels.weinhold@med.uni-heidelberg.de.; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany. niels.weinhold@med.uni-heidelberg.de.; Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA. niels.weinhold@med.uni-heidelberg.de. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2023 Aug 17; Vol. 14 (1), pp. 5011. <i>Date of Electronic Publication: </i>2023 Aug 17. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. 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