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MCL1 inhibition targets Myeloid Derived Suppressors Cells, promotes antitumor immunity and enhances the efficacy of immune checkpoint blockade.

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Title: MCL1 inhibition targets Myeloid Derived Suppressors Cells, promotes antitumor immunity and enhances the efficacy of immune checkpoint blockade.
Authors: Mukherjee N; University of Colorado Anschutz Medical Campus, School of Medicine, Department of Dermatology, Aurora, CO, 80045, USA., Katsnelson E; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Surgical Oncology, Aurora, CO, 80045, USA., Brunetti TM; Department of Immunology & Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; University of Colorado Cancer Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Michel K; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Medical Oncology, Aurora, CO, 80045, USA., Couts KL; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Medical Oncology, Aurora, CO, 80045, USA., Lambert KA; University of Colorado Anschutz Medical Campus, School of Medicine, Department of Dermatology, Aurora, CO, 80045, USA., Robinson WA; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Medical Oncology, Aurora, CO, 80045, USA., McCarter MD; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Surgical Oncology, Aurora, CO, 80045, USA., Norris DA; University of Colorado Anschutz Medical Campus, School of Medicine, Department of Dermatology, Aurora, CO, 80045, USA.; Department of Veterans Affairs Medical Center, Dermatology Section, Denver, CO, 80220, USA., Tobin RP; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Surgical Oncology, Aurora, CO, 80045, USA. Richard.Tobin@cuanschutz.edu., Shellman YG; University of Colorado Anschutz Medical Campus, School of Medicine, Department of Dermatology, Aurora, CO, 80045, USA. Yiqun.shellman@CUAnschutz.edu.; University of Colorado Anschutz Medical Campus, Gates Center for Regenerative Medicine, Aurora, CO, 80045, USA. Yiqun.shellman@CUAnschutz.edu.
Source: Cell death & disease [Cell Death Dis] 2024 Mar 08; Vol. 15 (3), pp. 198. Date of Electronic Publication: 2024 Mar 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: MCL1 inhibition targets Myeloid Derived Suppressors Cells, promotes antitumor immunity and enhances the efficacy of immune checkpoint blockade.
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  Data: <searchLink fieldCode="AU" term="%22Mukherjee+N%22">Mukherjee N</searchLink>; University of Colorado Anschutz Medical Campus, School of Medicine, Department of Dermatology, Aurora, CO, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Katsnelson+E%22">Katsnelson E</searchLink>; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Surgical Oncology, Aurora, CO, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Brunetti+TM%22">Brunetti TM</searchLink>; Department of Immunology & Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; University of Colorado Cancer Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Michel+K%22">Michel K</searchLink>; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Medical Oncology, Aurora, CO, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Couts+KL%22">Couts KL</searchLink>; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Medical Oncology, Aurora, CO, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Lambert+KA%22">Lambert KA</searchLink>; University of Colorado Anschutz Medical Campus, School of Medicine, Department of Dermatology, Aurora, CO, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Robinson+WA%22">Robinson WA</searchLink>; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Medical Oncology, Aurora, CO, 80045, USA.<br /><searchLink fieldCode="AU" term="%22McCarter+MD%22">McCarter MD</searchLink>; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Surgical Oncology, Aurora, CO, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Norris+DA%22">Norris DA</searchLink>; University of Colorado Anschutz Medical Campus, School of Medicine, Department of Dermatology, Aurora, CO, 80045, USA.; Department of Veterans Affairs Medical Center, Dermatology Section, Denver, CO, 80220, USA.<br /><searchLink fieldCode="AU" term="%22Tobin+RP%22">Tobin RP</searchLink>; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Surgical Oncology, Aurora, CO, 80045, USA. Richard.Tobin@cuanschutz.edu.<br /><searchLink fieldCode="AU" term="%22Shellman+YG%22">Shellman YG</searchLink>; University of Colorado Anschutz Medical Campus, School of Medicine, Department of Dermatology, Aurora, CO, 80045, USA. Yiqun.shellman@CUAnschutz.edu.; University of Colorado Anschutz Medical Campus, Gates Center for Regenerative Medicine, Aurora, CO, 80045, USA. Yiqun.shellman@CUAnschutz.edu.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2024 Mar 08; Vol. 15 (3), pp. 198. <i>Date of Electronic Publication: </i>2024 Mar 08.
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