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Preexisting maternal immunity to AAV but not Cas9 impairs in utero gene editing in mice.

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Title: Preexisting maternal immunity to AAV but not Cas9 impairs in utero gene editing in mice.
Authors: Riley JS; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Luks VL; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Berkowitz CL; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Dumitru AM; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Kus NJ; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Dave A; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Menon P; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., De Paepe ME; Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, USA., Jain R; Division of Cardiology, Department of Medicine, and., Li L; Division of Cardiology, Department of Medicine, and., Dugoff L; Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Teefey CP; Center for Fetal Diagnosis and Treatment and., Alameh MG; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Zoltick PW; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Peranteau WH; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Center for Fetal Diagnosis and Treatment and.
Source: The Journal of clinical investigation [J Clin Invest] 2024 May 09; Vol. 134 (12). Date of Electronic Publication: 2024 May 09.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Preexisting maternal immunity to AAV but not Cas9 impairs in utero gene editing in mice.
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  Data: <searchLink fieldCode="AU" term="%22Riley+JS%22">Riley JS</searchLink>; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Luks+VL%22">Luks VL</searchLink>; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Berkowitz+CL%22">Berkowitz CL</searchLink>; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Dumitru+AM%22">Dumitru AM</searchLink>; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Kus+NJ%22">Kus NJ</searchLink>; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Dave+A%22">Dave A</searchLink>; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Menon+P%22">Menon P</searchLink>; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22De+Paepe+ME%22">De Paepe ME</searchLink>; Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, USA.<br /><searchLink fieldCode="AU" term="%22Jain+R%22">Jain R</searchLink>; Division of Cardiology, Department of Medicine, and.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Division of Cardiology, Department of Medicine, and.<br /><searchLink fieldCode="AU" term="%22Dugoff+L%22">Dugoff L</searchLink>; Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Teefey+CP%22">Teefey CP</searchLink>; Center for Fetal Diagnosis and Treatment and.<br /><searchLink fieldCode="AU" term="%22Alameh+MG%22">Alameh MG</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Zoltick+PW%22">Zoltick PW</searchLink>; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Peranteau+WH%22">Peranteau WH</searchLink>; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Center for Fetal Diagnosis and Treatment and.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2024 May 09; Vol. 134 (12). <i>Date of Electronic Publication: </i>2024 May 09.
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        Value: 10.1172/JCI179848
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        Text: English
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              Text: 2024 May 09
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