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FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques.

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Title: FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques.
Authors: Zikos J; Nonhuman Primate Reagent Resource (NHPRR), Department of Medicine - Innate Immunity, UMass Chan Medical School, Worcester, MA, USA., Webb GM; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA., Wu HL; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA., Reed JS; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA., Watanabe J; California National Primate Research Center (CNPRC), University of California, Davis, CA, USA., Usachenko JL; California National Primate Research Center (CNPRC), University of California, Davis, CA, USA., Shaqra AM; Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester, MA, USA., Schiffer CA; Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester, MA, USA., Van Rompay KKA; California National Primate Research Center (CNPRC), University of California, Davis, CA, USA.; Department of Pathology, Microbiology and Immunology, University of California, Davis, CA, USA., Sacha JB; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA., Magnani DM; Nonhuman Primate Reagent Resource (NHPRR), Department of Medicine - Innate Immunity, UMass Chan Medical School, Worcester, MA, USA.
Source: MAbs [MAbs] 2024 Jan-Dec; Vol. 16 (1), pp. 2406788. Date of Electronic Publication: 2024 Sep 26.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques.
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  Data: <searchLink fieldCode="AU" term="%22Zikos+J%22">Zikos J</searchLink>; Nonhuman Primate Reagent Resource (NHPRR), Department of Medicine - Innate Immunity, UMass Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Webb+GM%22">Webb GM</searchLink>; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Wu+HL%22">Wu HL</searchLink>; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Reed+JS%22">Reed JS</searchLink>; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Watanabe+J%22">Watanabe J</searchLink>; California National Primate Research Center (CNPRC), University of California, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Usachenko+JL%22">Usachenko JL</searchLink>; California National Primate Research Center (CNPRC), University of California, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Shaqra+AM%22">Shaqra AM</searchLink>; Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Schiffer+CA%22">Schiffer CA</searchLink>; Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Van+Rompay+KKA%22">Van Rompay KKA</searchLink>; California National Primate Research Center (CNPRC), University of California, Davis, CA, USA.; Department of Pathology, Microbiology and Immunology, University of California, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sacha+JB%22">Sacha JB</searchLink>; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Magnani+DM%22">Magnani DM</searchLink>; Nonhuman Primate Reagent Resource (NHPRR), Department of Medicine - Innate Immunity, UMass Chan Medical School, Worcester, MA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101479829%22">MAbs</searchLink> [MAbs] 2024 Jan-Dec; Vol. 16 (1), pp. 2406788. <i>Date of Electronic Publication: </i>2024 Sep 26.
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