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Transglutaminase 2 promotes epithelial-to-mesenchymal transition by regulating the expression of matrix metalloproteinase 7 in colorectal cancer cells via the MEK/ERK signaling pathway.

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Title: Transglutaminase 2 promotes epithelial-to-mesenchymal transition by regulating the expression of matrix metalloproteinase 7 in colorectal cancer cells via the MEK/ERK signaling pathway.
Authors: Blaheta RA; University Medical Center Mainz, Dept. of Urology and Pediatric Urology, 55131 Mainz, Germany. Electronic address: roman.blaheta@unimedizin-mainz.de., Han J; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany., Oppermann E; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany., Bechstein WO; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany., Burkhard K; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany; Current affiliation: Department of Legal Medicine, University of Saarland Medical School, 66421 Homburg, Germany., Haferkamp A; University Medical Center Mainz, Dept. of Urology and Pediatric Urology, 55131 Mainz, Germany., Rieger MA; Department of Medicine II, Hematology/Oncology, Goethe University, 60590 Frankfurt am Main, Germany; Cardio-Pulmonary-Institute, 60590 Frankfurt am Main, Germany; Frankfurt Cancer Institute, 60590 Frankfurt am Main, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Malkomes P; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany; Frankfurt Cancer Institute, 60590 Frankfurt am Main, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Source: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2025 Jan; Vol. 1871 (1), pp. 167538. Date of Electronic Publication: 2024 Oct 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-260X (Electronic) Linking ISSN: 09254439 NLM ISO Abbreviation: Biochim Biophys Acta Mol Basis Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Transglutaminase 2 promotes epithelial-to-mesenchymal transition by regulating the expression of matrix metalloproteinase 7 in colorectal cancer cells via the MEK/ERK signaling pathway.
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  Data: <searchLink fieldCode="AU" term="%22Blaheta+RA%22">Blaheta RA</searchLink>; University Medical Center Mainz, Dept. of Urology and Pediatric Urology, 55131 Mainz, Germany. Electronic address: roman.blaheta@unimedizin-mainz.de.<br /><searchLink fieldCode="AU" term="%22Han+J%22">Han J</searchLink>; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Oppermann+E%22">Oppermann E</searchLink>; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Bechstein+WO%22">Bechstein WO</searchLink>; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Burkhard+K%22">Burkhard K</searchLink>; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany; Current affiliation: Department of Legal Medicine, University of Saarland Medical School, 66421 Homburg, Germany.<br /><searchLink fieldCode="AU" term="%22Haferkamp+A%22">Haferkamp A</searchLink>; University Medical Center Mainz, Dept. of Urology and Pediatric Urology, 55131 Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Rieger+MA%22">Rieger MA</searchLink>; Department of Medicine II, Hematology/Oncology, Goethe University, 60590 Frankfurt am Main, Germany; Cardio-Pulmonary-Institute, 60590 Frankfurt am Main, Germany; Frankfurt Cancer Institute, 60590 Frankfurt am Main, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Malkomes+P%22">Malkomes P</searchLink>; Department for General, Visceral, Transplant and Thoracic Surgery, Goethe University, 60590 Frankfurt am Main, Germany; Frankfurt Cancer Institute, 60590 Frankfurt am Main, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101731730%22">Biochimica et biophysica acta. Molecular basis of disease</searchLink> [Biochim Biophys Acta Mol Basis Dis] 2025 Jan; Vol. 1871 (1), pp. 167538. <i>Date of Electronic Publication: </i>2024 Oct 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101731730 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-260X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209254439%22">09254439 </searchLink><i>NLM ISO Abbreviation: </i>Biochim Biophys Acta Mol Basis Dis <i>Subsets: </i>MEDLINE
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              Text: 2025 Jan
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