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Vasculogenic skin reprogramming requires TET-mediated gene demethylation in fibroblasts for rescuing impaired perfusion in diabetes.

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Title: Vasculogenic skin reprogramming requires TET-mediated gene demethylation in fibroblasts for rescuing impaired perfusion in diabetes.
Authors: Mohanty SK; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Singh K; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Kumar M; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Verma SS; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Srivastava R; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Gnyawali SC; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Palakurti R; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Sahi AK; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA., El Masry MS; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Banerjee P; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Kacar S; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Rustagi Y; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Verma P; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Ghatak S; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Hernandez E; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Rubin JP; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA., Khanna S; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Roy S; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Yoder MC; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA., Sen CK; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA. c.k.sen@pitt.edu.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA. c.k.sen@pitt.edu.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA. c.k.sen@pitt.edu.; Department of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA, USA. c.k.sen@pitt.edu.
Source: Nature communications [Nat Commun] 2024 Nov 27; Vol. 15 (1), pp. 10277. Date of Electronic Publication: 2024 Nov 27.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Vasculogenic skin reprogramming requires TET-mediated gene demethylation in fibroblasts for rescuing impaired perfusion in diabetes.
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  Data: <searchLink fieldCode="AU" term="%22Mohanty+SK%22">Mohanty SK</searchLink>; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Singh+K%22">Singh K</searchLink>; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Kumar+M%22">Kumar M</searchLink>; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Verma+SS%22">Verma SS</searchLink>; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Srivastava+R%22">Srivastava R</searchLink>; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Gnyawali+SC%22">Gnyawali SC</searchLink>; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Palakurti+R%22">Palakurti R</searchLink>; 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Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Rustagi+Y%22">Rustagi Y</searchLink>; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Verma+P%22">Verma P</searchLink>; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Ghatak+S%22">Ghatak S</searchLink>; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Hernandez+E%22">Hernandez E</searchLink>; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Rubin+JP%22">Rubin JP</searchLink>; 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McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Sen+CK%22">Sen CK</searchLink>; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA. c.k.sen@pitt.edu.; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA. c.k.sen@pitt.edu.; Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA. c.k.sen@pitt.edu.; Department of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA, USA. c.k.sen@pitt.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2024 Nov 27; Vol. 15 (1), pp. 10277. <i>Date of Electronic Publication: </i>2024 Nov 27.
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