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Risk analysis for outpatient experimental infection as a pathway for affordable RSV vaccine development.

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Title: Risk analysis for outpatient experimental infection as a pathway for affordable RSV vaccine development.
Authors: Siegal EZ; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Schoevers JMH; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Terstappen J; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; Center for Translational Immunology (CTI), Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Delemarre EM; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; Center for Translational Immunology (CTI), Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Johnston SL; Virtus Respiratory Research Ltd, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., van Beek LF; Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases, Radboud university medical Center, Nijmegen, The Netherlands., Bogaert D; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK., Chiu C; Virtus Respiratory Research Ltd, London, UK., Diavatopoulos DA; Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands., Ferreira DM; Oxford Vaccine Group, Department of Paediatrics, The NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., Gordon SB; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., Hayden FG; Division of infectious Diseases and International Health, University of Virginia, School of Medicine, Charlottesville, VA, USA., de Jonge MI; Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases, Radboud university medical Center, Nijmegen, The Netherlands., McCall MBB; Radboud Center for Infectious Diseases, Radboud university medical Center, Nijmegen, The Netherlands., McShane HI; Oxford Vaccine Group, Department of Paediatrics, The NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Minassian AM; Oxford Vaccine Group, Department of Paediatrics, The NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Department of Biochemistry, University of Oxford, Oxford, UK., Openshaw PJM; National Heart and Lung Institute, Imperial College London, London, UK., Pollard AJ; Oxford Vaccine Group, Department of Paediatrics, The NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., Sattabongkot J; Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Read RC; Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK., Troelstra A; Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands., Viveen MC; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Wilder-Smith A; Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany., van Wijk M; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Bont LJ; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; Respiratory Syncytial Virus Network (ReSViNET), Utrecht, The Netherlands., Mazur NI; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands. n.i.mazur@umcutrecht.nl.; Center for Translational Immunology (CTI), Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands. n.i.mazur@umcutrecht.nl.; Department of Pediatrics, St. Antonius Hospital, Nieuwegein, The Netherlands. n.i.mazur@umcutrecht.nl.
Source: NPJ vaccines [NPJ Vaccines] 2025 Apr 15; Vol. 10 (1), pp. 70. Date of Electronic Publication: 2025 Apr 15.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Risk analysis for outpatient experimental infection as a pathway for affordable RSV vaccine development.
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  Data: <searchLink fieldCode="AU" term="%22Siegal+EZ%22">Siegal EZ</searchLink>; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Schoevers+JMH%22">Schoevers JMH</searchLink>; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Terstappen+J%22">Terstappen J</searchLink>; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; Center for Translational Immunology (CTI), Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Delemarre+EM%22">Delemarre EM</searchLink>; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; Center for Translational Immunology (CTI), Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Johnston+SL%22">Johnston SL</searchLink>; Virtus Respiratory Research Ltd, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22van+Beek+LF%22">van Beek LF</searchLink>; Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases, Radboud university medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bogaert+D%22">Bogaert D</searchLink>; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Chiu+C%22">Chiu C</searchLink>; Virtus Respiratory Research Ltd, London, UK.<br /><searchLink fieldCode="AU" term="%22Diavatopoulos+DA%22">Diavatopoulos DA</searchLink>; Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ferreira+DM%22">Ferreira DM</searchLink>; Oxford Vaccine Group, Department of Paediatrics, The NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Gordon+SB%22">Gordon SB</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Hayden+FG%22">Hayden FG</searchLink>; Division of infectious Diseases and International Health, University of Virginia, School of Medicine, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22de+Jonge+MI%22">de Jonge MI</searchLink>; Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases, Radboud university medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22McCall+MBB%22">McCall MBB</searchLink>; Radboud Center for Infectious Diseases, Radboud university medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22McShane+HI%22">McShane HI</searchLink>; Oxford Vaccine Group, Department of Paediatrics, The NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Minassian+AM%22">Minassian AM</searchLink>; Oxford Vaccine Group, Department of Paediatrics, The NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Department of Biochemistry, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Openshaw+PJM%22">Openshaw PJM</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Pollard+AJ%22">Pollard AJ</searchLink>; Oxford Vaccine Group, Department of Paediatrics, The NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Sattabongkot+J%22">Sattabongkot J</searchLink>; Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Read+RC%22">Read RC</searchLink>; Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Troelstra+A%22">Troelstra A</searchLink>; Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Viveen+MC%22">Viveen MC</searchLink>; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wilder-Smith+A%22">Wilder-Smith A</searchLink>; Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22van+Wijk+M%22">van Wijk M</searchLink>; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bont+LJ%22">Bont LJ</searchLink>; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; Respiratory Syncytial Virus Network (ReSViNET), Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mazur+NI%22">Mazur NI</searchLink>; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands. n.i.mazur@umcutrecht.nl.; Center for Translational Immunology (CTI), Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands. n.i.mazur@umcutrecht.nl.; Department of Pediatrics, St. Antonius Hospital, Nieuwegein, The Netherlands. n.i.mazur@umcutrecht.nl.
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  Data: <searchLink fieldCode="JN" term="%22101699863%22">NPJ vaccines</searchLink> [NPJ Vaccines] 2025 Apr 15; Vol. 10 (1), pp. 70. <i>Date of Electronic Publication: </i>2025 Apr 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature+in+partnership+with+the+Sealy+Center+for+Vaccine+Development%22">Springer Nature in partnership with the Sealy Center for Vaccine Development </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101699863 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-0105 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220590105%22">20590105 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Vaccines <i>Subsets: </i>PubMed not MEDLINE
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