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SAMD9 senses cytosolic double-stranded nucleic acids in epithelial and mesenchymal cells to induce antiviral immunity.

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Title: SAMD9 senses cytosolic double-stranded nucleic acids in epithelial and mesenchymal cells to induce antiviral immunity.
Authors: Hou G; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Beatty W; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Ren L; Department of Medicine, Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA.; Palo Alto Veterans Institute of Research, VA Palo Alto Health Care System, Palo Alto, CA, USA.; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, China., Ooi YS; Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA.; Emerging Infectious Diseases Program, Duke-NUS Medical School, Singapore, Singapore., Son J; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Zhu Y; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Sheng Q; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Huang W; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Li D; Division of Nephrology, Department of Medicine and Department of Developmental Biology, Washington University in St. Louis, St. Louis, MO, USA., Liu C; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Welsh OL; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA., Sutherland DM; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA., Dermody TS; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA., Shen C; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Liu J; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Sibley LD; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Ding S; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA. siyuan.ding@wustl.edu.
Source: Nature communications [Nat Commun] 2025 Apr 22; Vol. 16 (1), pp. 3756. Date of Electronic Publication: 2025 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: SAMD9 senses cytosolic double-stranded nucleic acids in epithelial and mesenchymal cells to induce antiviral immunity.
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  Data: <searchLink fieldCode="AU" term="%22Hou+G%22">Hou G</searchLink>; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Beatty+W%22">Beatty W</searchLink>; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Ren+L%22">Ren L</searchLink>; Department of Medicine, Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA.; Palo Alto Veterans Institute of Research, VA Palo Alto Health Care System, Palo Alto, CA, USA.; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Ooi+YS%22">Ooi YS</searchLink>; Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA.; Emerging Infectious Diseases Program, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Son+J%22">Son J</searchLink>; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+Y%22">Zhu Y</searchLink>; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Sheng+Q%22">Sheng Q</searchLink>; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Huang+W%22">Huang W</searchLink>; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; Division of Nephrology, Department of Medicine and Department of Developmental Biology, Washington University in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Welsh+OL%22">Welsh OL</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Sutherland+DM%22">Sutherland DM</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Dermody+TS%22">Dermody TS</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Shen+C%22">Shen C</searchLink>; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22Sibley+LD%22">Sibley LD</searchLink>; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Ding+S%22">Ding S</searchLink>; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA. siyuan.ding@wustl.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Apr 22; Vol. 16 (1), pp. 3756. <i>Date of Electronic Publication: </i>2025 Apr 22.
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