View in EDS

GIPR-Ab/GLP-1 peptide-antibody conjugate requires brain GIPR and GLP-1R for additive weight loss in obese mice.

Saved in:
Bibliographic Details
Title: GIPR-Ab/GLP-1 peptide-antibody conjugate requires brain GIPR and GLP-1R for additive weight loss in obese mice.
Authors: Liu CM; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA.; Amgen R&D Postdoctoral Fellows Program, Amgen Inc., Thousand Oaks, CA, USA., Killion EA; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA., Hammoud R; The Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, University of Toronto, Toronto, Ontario, Canada., Lu SC; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA., Komorowski R; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA., Liu T; Center for Research Acceleration by Digital Innovation, Amgen Research, Thousand Oaks, CA, USA., Kanke M; Department of Research Technologies, Amgen Research, South San Francisco, CA, USA., Thomas VA; Department of Pharmacokinetics and Drug Metabolism, Amgen Research, South San Francisco, CA, USA., Cook K; Department of Pharmacokinetics and Drug Metabolism, Amgen Research, South San Francisco, CA, USA., Sivits GN Jr; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA., Ben AB; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA., Atangan LI; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA., Hussien R; Department of Translational Safety and Bioanalytical Sciences, Amgen Research, South San Francisco, CA, USA., Tang A; Department of Translational Safety and Bioanalytical Sciences, Amgen Research, South San Francisco, CA, USA., Shkumatov A; Department of Translational Safety and Bioanalytical Sciences, Amgen Research, South San Francisco, CA, USA., Li CM; Department of Research Technologies, Amgen Research, South San Francisco, CA, USA., Drucker DJ; The Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, University of Toronto, Toronto, Ontario, Canada., Véniant MM; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA. mveniant@amgen.com.
Source: Nature metabolism [Nat Metab] 2025 Jun; Vol. 7 (6), pp. 1266-1281. Date of Electronic Publication: 2025 Apr 29.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40301582
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: GIPR-Ab/GLP-1 peptide-antibody conjugate requires brain GIPR and GLP-1R for additive weight loss in obese mice.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Liu+CM%22">Liu CM</searchLink>; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA.; Amgen R&D Postdoctoral Fellows Program, Amgen Inc., Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Killion+EA%22">Killion EA</searchLink>; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hammoud+R%22">Hammoud R</searchLink>; The Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Lu+SC%22">Lu SC</searchLink>; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Komorowski+R%22">Komorowski R</searchLink>; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Liu+T%22">Liu T</searchLink>; Center for Research Acceleration by Digital Innovation, Amgen Research, Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kanke+M%22">Kanke M</searchLink>; Department of Research Technologies, Amgen Research, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+VA%22">Thomas VA</searchLink>; Department of Pharmacokinetics and Drug Metabolism, Amgen Research, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cook+K%22">Cook K</searchLink>; Department of Pharmacokinetics and Drug Metabolism, Amgen Research, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sivits+GN+Jr%22">Sivits GN Jr</searchLink>; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ben+AB%22">Ben AB</searchLink>; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Atangan+LI%22">Atangan LI</searchLink>; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hussien+R%22">Hussien R</searchLink>; Department of Translational Safety and Bioanalytical Sciences, Amgen Research, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tang+A%22">Tang A</searchLink>; Department of Translational Safety and Bioanalytical Sciences, Amgen Research, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Shkumatov+A%22">Shkumatov A</searchLink>; Department of Translational Safety and Bioanalytical Sciences, Amgen Research, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Li+CM%22">Li CM</searchLink>; Department of Research Technologies, Amgen Research, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Drucker+DJ%22">Drucker DJ</searchLink>; The Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Véniant+MM%22">Véniant MM</searchLink>; Department of Cardiometabolic Disorders, Amgen Research, Thousand Oaks, CA, USA. mveniant@amgen.com.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101736592%22">Nature metabolism</searchLink> [Nat Metab] 2025 Jun; Vol. 7 (6), pp. 1266-1281. <i>Date of Electronic Publication: </i>2025 Apr 29.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101736592 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2522-5812 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225225812%22">25225812 </searchLink><i>NLM ISO Abbreviation: </i>Nat Metab <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40301582
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s42255-025-01295-w
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1266
    Titles:
      – TitleFull: GIPR-Ab/GLP-1 peptide-antibody conjugate requires brain GIPR and GLP-1R for additive weight loss in obese mice.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Liu CM
      – PersonEntity:
          Name:
            NameFull: Killion EA
      – PersonEntity:
          Name:
            NameFull: Hammoud R
      – PersonEntity:
          Name:
            NameFull: Lu SC
      – PersonEntity:
          Name:
            NameFull: Komorowski R
      – PersonEntity:
          Name:
            NameFull: Liu T
      – PersonEntity:
          Name:
            NameFull: Kanke M
      – PersonEntity:
          Name:
            NameFull: Thomas VA
      – PersonEntity:
          Name:
            NameFull: Cook K
      – PersonEntity:
          Name:
            NameFull: Sivits GN Jr
      – PersonEntity:
          Name:
            NameFull: Ben AB
      – PersonEntity:
          Name:
            NameFull: Atangan LI
      – PersonEntity:
          Name:
            NameFull: Hussien R
      – PersonEntity:
          Name:
            NameFull: Tang A
      – PersonEntity:
          Name:
            NameFull: Shkumatov A
      – PersonEntity:
          Name:
            NameFull: Li CM
      – PersonEntity:
          Name:
            NameFull: Drucker DJ
      – PersonEntity:
          Name:
            NameFull: Véniant MM
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 06
              Text: 2025 Jun
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2522-5812
          Numbering:
            – Type: volume
              Value: 7
            – Type: issue
              Value: 6
          Titles:
            – TitleFull: Nature metabolism
              Type: main
ResultId 1