A Novel Flavonoid Derivative of Icariside II (YS-10) Improves Erectile Dysfunction in a Diabetic Rat Model by Inhibiting Ferroptosis via Activation of the Nrf2/HO-1/GPX4 Pathway.
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| Title: | A Novel Flavonoid Derivative of Icariside II (YS-10) Improves Erectile Dysfunction in a Diabetic Rat Model by Inhibiting Ferroptosis via Activation of the Nrf2/HO-1/GPX4 Pathway. |
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| Authors: | Liu Y; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Liu GN; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Zha YR; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Pan CL; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Xu YD; Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China., Li HW; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Zang YY; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Wang WQ; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Yao JJ; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Sun JT; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Yang Y; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Wei ZT; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China. |
| Source: | Drug design, development and therapy [Drug Des Devel Ther] 2025 May 28; Vol. 19, pp. 4481-4500. Date of Electronic Publication: 2025 May 28 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40453214 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A Novel Flavonoid Derivative of Icariside II (YS-10) Improves Erectile Dysfunction in a Diabetic Rat Model by Inhibiting Ferroptosis via Activation of the Nrf2/HO-1/GPX4 Pathway. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Liu+GN%22">Liu GN</searchLink>; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zha+YR%22">Zha YR</searchLink>; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Pan+CL%22">Pan CL</searchLink>; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xu+YD%22">Xu YD</searchLink>; Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+HW%22">Li HW</searchLink>; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zang+YY%22">Zang YY</searchLink>; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+WQ%22">Wang WQ</searchLink>; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Yao+JJ%22">Yao JJ</searchLink>; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Sun+JT%22">Sun JT</searchLink>; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wei+ZT%22">Wei ZT</searchLink>; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101475745%22">Drug design, development and therapy</searchLink> [Drug Des Devel Ther] 2025 May 28; Vol. 19, pp. 4481-4500. <i>Date of Electronic Publication: </i>2025 May 28 (<i>Print Publication: </i>2025). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Dove+Press+Limited%22">Dove Press Limited </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>101475745 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1177-8881 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211778881%22">11778881 </searchLink><i>NLM ISO Abbreviation: </i>Drug Des Devel Ther <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40453214 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.2147/DDDT.S518992 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 4481 Titles: – TitleFull: A Novel Flavonoid Derivative of Icariside II (YS-10) Improves Erectile Dysfunction in a Diabetic Rat Model by Inhibiting Ferroptosis via Activation of the Nrf2/HO-1/GPX4 Pathway. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Liu Y – PersonEntity: Name: NameFull: Liu GN – PersonEntity: Name: NameFull: Zha YR – PersonEntity: Name: NameFull: Pan CL – PersonEntity: Name: NameFull: Xu YD – PersonEntity: Name: NameFull: Li HW – PersonEntity: Name: NameFull: Zang YY – PersonEntity: Name: NameFull: Wang WQ – PersonEntity: Name: NameFull: Yao JJ – PersonEntity: Name: NameFull: Sun JT – PersonEntity: Name: NameFull: Yang Y – PersonEntity: Name: NameFull: Wei ZT IsPartOfRelationships: – BibEntity: Dates: – D: 28 M: 05 Text: 2025 May 28 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1177-8881 Numbering: – Type: volume Value: 19 Titles: – TitleFull: Drug design, development and therapy Type: main |
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