Checkpoint antibody receptor modified ARMed CAR T circumvents the suppressive immunome in GBM.
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| Title: | Checkpoint antibody receptor modified ARMed CAR T circumvents the suppressive immunome in GBM. |
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| Authors: | Cook DR; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Boesteanu AC; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Yin Y; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.; Glioblastoma Translational Center of Excellence, Abramson Cancer Center and Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Reid R; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Roccograndi L; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Dahmane N; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Martinez-Lage M; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States., O'Rourke DM; Glioblastoma Translational Center of Excellence, Abramson Cancer Center and Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., June CH; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States., Johnson LA; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States. |
| Source: | Frontiers in immunology [Front Immunol] 2025 Jul 31; Vol. 16, pp. 1579925. Date of Electronic Publication: 2025 Jul 31 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2025.1579925 |