Anti-cathepsin D antibody-drug conjugates for the targeted delivery of monomethyl auristatin F and E elicit potent anticancer activity in breast cancer.
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| Title: | Anti-cathepsin D antibody-drug conjugates for the targeted delivery of monomethyl auristatin F and E elicit potent anticancer activity in breast cancer. |
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| Authors: | Nishimwe D; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France., Guillon G; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France., Mallavialle A; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France., Martin C; UMR 1100 CEPR, INSERM, University of Tours, Tours F-37200, France., Huvelle S; UMR 1100 CEPR, INSERM, University of Tours, Tours F-37200, France., Alcaraz LB; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France., Romero A; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France., Garapon C; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France., Garambois V; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France., Mansouri H; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France., Boissière-Michot F; Translational Research Unit, ICM, Montpellier, France., Berestjuk I; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France., Jarlier M; Biometry Department, ICM, Montpellier, France., Turtoi A; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France; Gunma University Initiative for Advanced Research, Maebashi, Gunma 371-0034, Japan., Denevault-Sabourin C; UMR 1100 CEPR, INSERM, University of Tours, Tours F-37200, France., Roger P; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France; Department of Pathology, CHU Nîmes, Nîmes, France., Guiu S; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France; Department of Medical Oncology, ICM, Montpellier, France., Chardès T; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France; CNRS, Centre national de la recherche Scientifique, Paris F-75016, France., Joubert N; UMR 1100 CEPR, INSERM, University of Tours, Tours F-37200, France., Laurent-Matha V; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France., Liaudet-Coopman E; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France. Electronic address: emmanuelle.liaudet-coopman@inserm.fr. |
| Source: | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 Dec; Vol. 193, pp. 118775. Date of Electronic Publication: 2025 Nov 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41242136 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Anti-cathepsin D antibody-drug conjugates for the targeted delivery of monomethyl auristatin F and E elicit potent anticancer activity in breast cancer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Nishimwe+D%22">Nishimwe D</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Guillon+G%22">Guillon G</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Mallavialle+A%22">Mallavialle A</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Martin+C%22">Martin C</searchLink>; UMR 1100 CEPR, INSERM, University of Tours, Tours F-37200, France.<br /><searchLink fieldCode="AU" term="%22Huvelle+S%22">Huvelle S</searchLink>; UMR 1100 CEPR, INSERM, University of Tours, Tours F-37200, France.<br /><searchLink fieldCode="AU" term="%22Alcaraz+LB%22">Alcaraz LB</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Romero+A%22">Romero A</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Garapon+C%22">Garapon C</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Garambois+V%22">Garambois V</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Mansouri+H%22">Mansouri H</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Boissière-Michot+F%22">Boissière-Michot F</searchLink>; Translational Research Unit, ICM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Berestjuk+I%22">Berestjuk I</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Jarlier+M%22">Jarlier M</searchLink>; Biometry Department, ICM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Turtoi+A%22">Turtoi A</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France; Gunma University Initiative for Advanced Research, Maebashi, Gunma 371-0034, Japan.<br /><searchLink fieldCode="AU" term="%22Denevault-Sabourin+C%22">Denevault-Sabourin C</searchLink>; UMR 1100 CEPR, INSERM, University of Tours, Tours F-37200, France.<br /><searchLink fieldCode="AU" term="%22Roger+P%22">Roger P</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France; Department of Pathology, CHU Nîmes, Nîmes, France.<br /><searchLink fieldCode="AU" term="%22Guiu+S%22">Guiu S</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France; Department of Medical Oncology, ICM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Chardès+T%22">Chardès T</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France; CNRS, Centre national de la recherche Scientifique, Paris F-75016, France.<br /><searchLink fieldCode="AU" term="%22Joubert+N%22">Joubert N</searchLink>; UMR 1100 CEPR, INSERM, University of Tours, Tours F-37200, France.<br /><searchLink fieldCode="AU" term="%22Laurent-Matha+V%22">Laurent-Matha V</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Liaudet-Coopman+E%22">Liaudet-Coopman E</searchLink>; IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France. Electronic address: emmanuelle.liaudet-coopman@inserm.fr. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228213295%22">Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie</searchLink> [Biomed Pharmacother] 2025 Dec; Vol. 193, pp. 118775. <i>Date of Electronic Publication: </i>2025 Nov 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Scientifiques+Elsevier%22">Editions Scientifiques Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>8213295 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1950-6007 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207533322%22">07533322 </searchLink><i>NLM ISO Abbreviation: </i>Biomed Pharmacother <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41242136 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.biopha.2025.118775 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 118775 Titles: – TitleFull: Anti-cathepsin D antibody-drug conjugates for the targeted delivery of monomethyl auristatin F and E elicit potent anticancer activity in breast cancer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Nishimwe D – PersonEntity: Name: NameFull: Guillon G – PersonEntity: Name: NameFull: Mallavialle A – PersonEntity: Name: NameFull: Martin C – PersonEntity: Name: NameFull: Huvelle S – PersonEntity: Name: NameFull: Alcaraz LB – PersonEntity: Name: NameFull: Romero A – PersonEntity: Name: NameFull: Garapon C – PersonEntity: Name: NameFull: Garambois V – PersonEntity: Name: NameFull: Mansouri H – PersonEntity: Name: NameFull: Boissière-Michot F – PersonEntity: Name: NameFull: Berestjuk I – PersonEntity: Name: NameFull: Jarlier M – PersonEntity: Name: NameFull: Turtoi A – PersonEntity: Name: NameFull: Denevault-Sabourin C – PersonEntity: Name: NameFull: Roger P – PersonEntity: Name: NameFull: Guiu S – PersonEntity: Name: NameFull: Chardès T – PersonEntity: Name: NameFull: Joubert N – PersonEntity: Name: NameFull: Laurent-Matha V – PersonEntity: Name: NameFull: Liaudet-Coopman E IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: 2025 Dec Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1950-6007 Numbering: – Type: volume Value: 193 Titles: – TitleFull: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Type: main |
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