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Transcriptional changes in non-human primate tissues after intrathecal delivery of serotype 9 adeno-associated viral vector: Insights into organ toxicities.

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Title: Transcriptional changes in non-human primate tissues after intrathecal delivery of serotype 9 adeno-associated viral vector: Insights into organ toxicities.
Authors: Aihara F; Novartis Biomedical Research, Cambridge, MA, USA., Mardo M; Novartis Biomedical Research, Cambridge, MA, USA., Ruda V; Novartis Biomedical Research, Cambridge, MA, USA., Rio TD; Novartis Biomedical Research, San Diego, CA, USA., Bigot K; Novartis Biomedical Research, Basel, Switzerland., Singer J; Novartis Biomedical Research, Basel, Switzerland., Onishi-Seebacher M; Novartis Biomedical Research, Basel, Switzerland., Couttet P; Novartis Biomedical Research, Basel, Switzerland., Mansfield K; Novartis Biomedical Research, Cambridge, MA, USA., Hudry E; Novartis Biomedical Research, Cambridge, MA, USA.
Source: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2025 Oct 16; Vol. 33 (4), pp. 101617. Date of Electronic Publication: 2025 Oct 16 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101624857 Publication Model: eCollection Cited Medium: Print ISSN: 2329-0501 (Print) Linking ISSN: 23290501 NLM ISO Abbreviation: Mol Ther Methods Clin Dev Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Transcriptional changes in non-human primate tissues after intrathecal delivery of serotype 9 adeno-associated viral vector: Insights into organ toxicities.
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  Data: <searchLink fieldCode="AU" term="%22Aihara+F%22">Aihara F</searchLink>; Novartis Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mardo+M%22">Mardo M</searchLink>; Novartis Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ruda+V%22">Ruda V</searchLink>; Novartis Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rio+TD%22">Rio TD</searchLink>; Novartis Biomedical Research, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bigot+K%22">Bigot K</searchLink>; Novartis Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Singer+J%22">Singer J</searchLink>; Novartis Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Onishi-Seebacher+M%22">Onishi-Seebacher M</searchLink>; Novartis Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Couttet+P%22">Couttet P</searchLink>; Novartis Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mansfield+K%22">Mansfield K</searchLink>; Novartis Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hudry+E%22">Hudry E</searchLink>; Novartis Biomedical Research, Cambridge, MA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101624857%22">Molecular therapy. Methods & clinical development</searchLink> [Mol Ther Methods Clin Dev] 2025 Oct 16; Vol. 33 (4), pp. 101617. <i>Date of Electronic Publication: </i>2025 Oct 16 (<i>Print Publication: </i>2025).
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        Value: 10.1016/j.omtm.2025.101617
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              Text: 2025 Oct 16
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