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HCV infection induces dysregulation of glucose-stimulated insulin secretion via the TLR3/TRIF/NF-κB-iNOS-NO axis: Implications for prediabetes in HCV patients.

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Title: HCV infection induces dysregulation of glucose-stimulated insulin secretion via the TLR3/TRIF/NF-κB-iNOS-NO axis: Implications for prediabetes in HCV patients.
Authors: Wang S; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China., Wu M; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China., Rong R; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China., Wang J; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China., Tursun K; The First Affiliated Hospital of Xinjiang Medical University, Urumchi, 830054, China., Ksimu S; The First Affiliated Hospital of Xinjiang Medical University, Urumchi, 830054, China., Zhou Y; Guangzhou Laboratory, Guangzhou, 510005, China., Wang N; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China. wangning@njmu.edu.cn., Wang Q; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China. wqian@njmu.edu.cn., Chen J; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510182, China. wqian@njmu.edu.cn.; Guangzhou Laboratory, Guangzhou, 510005, China. wqian@njmu.edu.cn.; State Key Laboratory of Virology, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China. wqian@njmu.edu.cn.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Apr 18; Vol. 83 (1). Date of Electronic Publication: 2026 Apr 18.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: HCV infection induces dysregulation of glucose-stimulated insulin secretion via the TLR3/TRIF/NF-κB-iNOS-NO axis: Implications for prediabetes in HCV patients.
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  Data: <searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China.<br /><searchLink fieldCode="AU" term="%22Wu+M%22">Wu M</searchLink>; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China.<br /><searchLink fieldCode="AU" term="%22Rong+R%22">Rong R</searchLink>; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China.<br /><searchLink fieldCode="AU" term="%22Tursun+K%22">Tursun K</searchLink>; The First Affiliated Hospital of Xinjiang Medical University, Urumchi, 830054, China.<br /><searchLink fieldCode="AU" term="%22Ksimu+S%22">Ksimu S</searchLink>; The First Affiliated Hospital of Xinjiang Medical University, Urumchi, 830054, China.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; Guangzhou Laboratory, Guangzhou, 510005, China.<br /><searchLink fieldCode="AU" term="%22Wang+N%22">Wang N</searchLink>; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China. wangning@njmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China. wqian@njmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510182, China. wqian@njmu.edu.cn.; Guangzhou Laboratory, Guangzhou, 510005, China. wqian@njmu.edu.cn.; State Key Laboratory of Virology, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China. wqian@njmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229705402%22">Cellular and molecular life sciences : CMLS</searchLink> [Cell Mol Life Sci] 2026 Apr 18; Vol. 83 (1). <i>Date of Electronic Publication: </i>2026 Apr 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>9705402 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1420-9071 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221420682X%22">1420682X </searchLink><i>NLM ISO Abbreviation: </i>Cell Mol Life Sci <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr 18
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