LRRC58 defines an E3 ubiquitin ligase complex sensitive to cysteine abundance.
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| Title: | LRRC58 defines an E3 ubiquitin ligase complex sensitive to cysteine abundance. |
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| Authors: | Ramage DE; Cambridge Institute for Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Puddicombe Way, Cambridge, UK., Wieske LHE; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, Dundee, UK., Crowe C; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, Dundee, UK., Christensen JB; The Gurdon Institute, University of Cambridge, Cambridge, UK; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., von Wilmowski TA; Cambridge Institute for Medical Research, Department of Medicine, University of Cambridge, Cambridge, UK., Bannister Z; Cambridge Institute for Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Puddicombe Way, Cambridge, UK., Grant DW; Cambridge Institute for Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Puddicombe Way, Cambridge, UK., Nakasone MA; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, Dundee, UK., Haubrich K; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, Dundee, UK., Dorward M; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, Dundee, UK., Tchasovnikarova IA; The Gurdon Institute, University of Cambridge, Cambridge, UK; Department of Biochemistry, University of Cambridge, Cambridge, UK., Weekes MP; Cambridge Institute for Medical Research, Department of Medicine, University of Cambridge, Cambridge, UK., Matheson NJ; Cambridge Institute for Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Puddicombe Way, Cambridge, UK; NHS Blood and Transplant, Cambridge, UK., Bayin NS; The Gurdon Institute, University of Cambridge, Cambridge, UK; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Ciulli A; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, Dundee, UK., Timms RT; Cambridge Institute for Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Puddicombe Way, Cambridge, UK. Electronic address: rtt20@cam.ac.uk. |
| Source: | Molecular cell [Mol Cell] 2026 Jul 16; Vol. 86 (14), pp. 2828-2842.e12. Date of Electronic Publication: 2026 Jun 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42320481 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: LRRC58 defines an E3 ubiquitin ligase complex sensitive to cysteine abundance. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ramage+DE%22">Ramage DE</searchLink>; Cambridge Institute for Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Puddicombe Way, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Wieske+LHE%22">Wieske LHE</searchLink>; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Crowe+C%22">Crowe C</searchLink>; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Christensen+JB%22">Christensen JB</searchLink>; The Gurdon Institute, University of Cambridge, Cambridge, UK; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22von+Wilmowski+TA%22">von Wilmowski TA</searchLink>; Cambridge Institute for Medical Research, Department of Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Bannister+Z%22">Bannister Z</searchLink>; Cambridge Institute for Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Puddicombe Way, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Grant+DW%22">Grant DW</searchLink>; Cambridge Institute for Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Puddicombe Way, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Nakasone+MA%22">Nakasone MA</searchLink>; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Haubrich+K%22">Haubrich K</searchLink>; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Dorward+M%22">Dorward M</searchLink>; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Tchasovnikarova+IA%22">Tchasovnikarova IA</searchLink>; The Gurdon Institute, University of Cambridge, Cambridge, UK; Department of Biochemistry, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Weekes+MP%22">Weekes MP</searchLink>; Cambridge Institute for Medical Research, Department of Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Matheson+NJ%22">Matheson NJ</searchLink>; Cambridge Institute for Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Puddicombe Way, Cambridge, UK; NHS Blood and Transplant, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Bayin+NS%22">Bayin NS</searchLink>; The Gurdon Institute, University of Cambridge, Cambridge, UK; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Ciulli+A%22">Ciulli A</searchLink>; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Timms+RT%22">Timms RT</searchLink>; Cambridge Institute for Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Puddicombe Way, Cambridge, UK. Electronic address: rtt20@cam.ac.uk. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229802571%22">Molecular cell</searchLink> [Mol Cell] 2026 Jul 16; Vol. 86 (14), pp. 2828-2842.e12. <i>Date of Electronic Publication: </i>2026 Jun 19. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9802571 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-4164 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210972765%22">10972765 </searchLink><i>NLM ISO Abbreviation: </i>Mol Cell <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42320481 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.molcel.2026.06.014 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2828 Titles: – TitleFull: LRRC58 defines an E3 ubiquitin ligase complex sensitive to cysteine abundance. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ramage DE – PersonEntity: Name: NameFull: Wieske LHE – PersonEntity: Name: NameFull: Crowe C – PersonEntity: Name: NameFull: Christensen JB – PersonEntity: Name: NameFull: von Wilmowski TA – PersonEntity: Name: NameFull: Bannister Z – PersonEntity: Name: NameFull: Grant DW – PersonEntity: Name: NameFull: Nakasone MA – PersonEntity: Name: NameFull: Haubrich K – PersonEntity: Name: NameFull: Dorward M – PersonEntity: Name: NameFull: Tchasovnikarova IA – PersonEntity: Name: NameFull: Weekes MP – PersonEntity: Name: NameFull: Matheson NJ – PersonEntity: Name: NameFull: Bayin NS – PersonEntity: Name: NameFull: Ciulli A – PersonEntity: Name: NameFull: Timms RT IsPartOfRelationships: – BibEntity: Dates: – D: 16 M: 07 Text: 2026 Jul 16 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1097-4164 Numbering: – Type: volume Value: 86 – Type: issue Value: 14 Titles: – TitleFull: Molecular cell Type: main |
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