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Application of chimeric mice with human hepatocytes for the evaluation of metabolically activated genotoxic substances.

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Title: Application of chimeric mice with human hepatocytes for the evaluation of metabolically activated genotoxic substances.
Authors: Fujikawa M; Advanced Research Laboratory for Fundamental Technologies, Sumitomo Chemical Co., Ltd., 1-98, Kasugadenaka 3-chome, Konohana-ku, Osaka, 554-8558, Japan. fujikawam2@sc.sumitomo-chem.co.jp., Matsuyama R; Advanced Research Laboratory for Fundamental Technologies, Sumitomo Chemical Co., Ltd., 1-98, Kasugadenaka 3-chome, Konohana-ku, Osaka, 554-8558, Japan., Yamasaki C; PhoenixBio Co., Ltd., 3-4-1, Kagamiyama, Higashi-Hiroshima, 739-0046, Japan., Tateno C; PhoenixBio Co., Ltd., 3-4-1, Kagamiyama, Higashi-Hiroshima, 739-0046, Japan.; Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2- 3, Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.; School of Pharmaceutical Sciences, Wakayama Medical University, 25-1, Shichibancho, Wakayama, 640-8156, Japan., Asano H; Advanced Research Laboratory for Fundamental Technologies, Sumitomo Chemical Co., Ltd., 1-98, Kasugadenaka 3-chome, Konohana-ku, Osaka, 554-8558, Japan.
Source: Genes and environment : the official journal of the Japanese Environmental Mutagen Society [Genes Environ] 2026 Jun 19. Date of Electronic Publication: 2026 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101285347 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1880-7046 (Print) Linking ISSN: 18807046 NLM ISO Abbreviation: Genes Environ
Database: MEDLINE Ultimate
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  Data: Application of chimeric mice with human hepatocytes for the evaluation of metabolically activated genotoxic substances.
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  Data: <searchLink fieldCode="AU" term="%22Fujikawa+M%22">Fujikawa M</searchLink>; Advanced Research Laboratory for Fundamental Technologies, Sumitomo Chemical Co., Ltd., 1-98, Kasugadenaka 3-chome, Konohana-ku, Osaka, 554-8558, Japan. fujikawam2@sc.sumitomo-chem.co.jp.<br /><searchLink fieldCode="AU" term="%22Matsuyama+R%22">Matsuyama R</searchLink>; Advanced Research Laboratory for Fundamental Technologies, Sumitomo Chemical Co., Ltd., 1-98, Kasugadenaka 3-chome, Konohana-ku, Osaka, 554-8558, Japan.<br /><searchLink fieldCode="AU" term="%22Yamasaki+C%22">Yamasaki C</searchLink>; PhoenixBio Co., Ltd., 3-4-1, Kagamiyama, Higashi-Hiroshima, 739-0046, Japan.<br /><searchLink fieldCode="AU" term="%22Tateno+C%22">Tateno C</searchLink>; PhoenixBio Co., Ltd., 3-4-1, Kagamiyama, Higashi-Hiroshima, 739-0046, Japan.; Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2- 3, Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.; School of Pharmaceutical Sciences, Wakayama Medical University, 25-1, Shichibancho, Wakayama, 640-8156, Japan.<br /><searchLink fieldCode="AU" term="%22Asano+H%22">Asano H</searchLink>; Advanced Research Laboratory for Fundamental Technologies, Sumitomo Chemical Co., Ltd., 1-98, Kasugadenaka 3-chome, Konohana-ku, Osaka, 554-8558, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101285347%22">Genes and environment : the official journal of the Japanese Environmental Mutagen Society</searchLink> [Genes Environ] 2026 Jun 19. <i>Date of Electronic Publication: </i>2026 Jun 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101285347 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1880-7046 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218807046%22">18807046 </searchLink><i>NLM ISO Abbreviation: </i>Genes Environ
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        Value: 10.1186/s41021-026-00362-2
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      – TitleFull: Application of chimeric mice with human hepatocytes for the evaluation of metabolically activated genotoxic substances.
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            NameFull: Fujikawa M
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            – D: 19
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              Text: 2026 Jun 19
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